If the level of pain increases after dosage stabilization, attempt to identify the source of increased pain before increasing the Demerol Injection dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between management of pain and opioid-related adverse reactions. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Check the labels on all your medicines such as allergy or cough-and-cold products because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. cheapest toprol purchase store canada toprol
This medication contains tolterodine. Do not take Detrol or Detrol LA if you are allergic to tolterodine or any ingredients contained in this drug. The concomitant use of acyclovir may increase the plasma concentrations of meperidine and its metabolite, normeperidine. Drinking alcohol can increase some of the side effects of tolterodine. Studies in animals to evaluate the mutagenic potential of meperidine have not been conducted.
What Are Warnings and Precautions for Tolterodine? Parenteral drug products should be inspected visually for particulate and discoloration prior to administration whenever solution and container permit. Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use. The concomitant use of Demerol Injection and CYP3A4 or CYP2B6 inhibitors can increase the plasma concentration of meperidine, resulting in increased or prolonged opioid effects.
Check the Rx Outreach website for the exact price and most current medication list. The following adverse reactions associated with the use of meperidine were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Do NOT change your dose of Detrol LA extended-release capsules without checking with your doctor.
Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I miss a dose Detrol LA? This means you have any two types of the condition. Many women have both stress and urge incontinence. Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. Intravenous hydrocortisone or prednisolone have been used to treat severe reactions, with the addition of intravenous chlorpromazine in those cases exhibiting hypertension and hyperpyrexia. The usefulness and safety of narcotic antagonists in the treatment of these reactions is unknown. Do not stop taking this medication without consulting your doctor. Blunt cannulas should not be recapped, purposely bent or broken by hand. The safety and efficacy of Demerol Injection in patients less than 18 years of age have not been established. Meperidine is contraindicated in patients who are receiving monoamine oxidase MAO inhibitors or those who have recently received such agents. Therapeutic doses of meperidine have occasionally precipitated unpredictable, severe, and occasionally fatal reactions in patients who have received such agents within 14 days. The mechanism of these reactions is unclear, but may be related to a preexisting hyperphenylalaninemia. Some have been characterized by coma, severe respiratory depression, cyanosis, and hypotension, and have resembled the syndrome of acute narcotic overdose. Serotonin syndrome with agitation, hyperthermia, diarrhea, tachycardia, sweating, tremors and impaired consciousness may also occur. In other reactions the predominant manifestations have been hyperexcitability, convulsions, tachycardia, hyperpyrexia, and hypertension. If any of these effects persists or worsens, tell your doctor or promptly. The use of Demerol Injection in patients with acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment is contraindicated. Adults: The usual dosage is 50 mg to 150 mg intramuscularly or subcutaneously every 3 or 4 hours as needed for pain. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely.
QTdrugs List, AZCERT, Inc. Demerol Injection, like other opioids, can be diverted for non-medical use into illicit channels of distribution. Careful record-keeping of prescribing information, including quantity, frequency, and renewal requests, as required by state and federal law, is strongly advised. Surgery: Another way doctors can get rid of a kidney stone is to cut a small hole in your back and through your kidney in order to remove the stone. If this procedure is done, you could have to stay in the hospital for several days. Swallow this medication with the help of liquids. not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or tells you to do so. Swallow the whole or split tablet without crushing or chewing. Limit dosage and duration to the minimum required. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. How should I take tolterodine Detrol? DEMEROL meperidine hydrochloride, USP Injection is an opioid agonist, available for intramuscular, intravenous, or subcutaneous administration. Prolonged use of Demerol Injection during pregnancy can result in withdrawal in the neonate. Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Symptoms may include difficulty breathing; difficulty urinating; dilated pupils; dry mouth; excitation; fast heartbeat; hallucinations; seizures. It is not known whether this drug passes into milk. Consult your doctor before -feeding. In case of overdose, priorities are the reestablishment of a patent and protected airway and institution of assisted or controlled ventilation, if needed. Employ other supportive measures including oxygen and vasopressors in the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require advanced life-support techniques. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. cyproheptadine
Take this medication with water. If any of these effects persist or worsen, notify your doctor or promptly. Pfizer also has programs that provide eligible patients with insurance support, copay assistance, and medicines for free. Tell your doctor if your condition persists or worsens. Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. If your symptoms do not improve or if they become worse, check with your doctor. Demerol Injection may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery. Warn patients not to drive or operate dangerous machinery unless they are tolerant to the effects of Demerol Injection and know how they will react to the medication. Intravenous hydrocortisone or prednisolone have been used to treat severe reactions, with the addition of intravenous chlorpromazine in those cases exhibiting hypertension and hyperpyrexia. The usefulness and safety of narcotic antagonists in the treatment of these reactions is unknown. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. The meperidine in Demerol Injection may cause spasm of the sphincter of Oddi. Opioids may cause increases in serum amylase. Monitor patients with biliary tract disease, including acute pancreatitis, for worsening symptoms.
Opioids are sought by drug abusers and people with addiction disorders and are subject to criminal diversion. Consider these risks when prescribing or dispensing Demerol Injection. Strategies to reduce these risks include prescribing the drug in the smallest appropriate quantity. Take Detrol LA extended-release capsules by mouth with or without food. Follow patients for signs and symptoms of respiratory depression and sedation. Medications, electrical stimulation, or surgery. Doctors sometimes prescribe medicines that block the of an overactive bladder. Electrical stimulation of the bladder nerves helps in some cases. Surgery is reserved for severe cases. It aims to increase the amount of urine your bladder can store. Shock wave lithotripsy: This is the most common procedure for kidney stones in the United States. It uses shock waves, which can blast the stone into little pieces. Then, the smaller pieces can more easily be passed in your urine. Assess each patient's risk for opioid addiction, abuse, or misuse prior to prescribing Demerol Injection, and monitor all patients receiving Demerol Injection for the development of these behaviors and conditions. This product may increase your potassium levels. Before using potassium or salt substitutes that contain potassium, consult your doctor or pharmacist. Demerol Injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Acute overdose with Demerol Injection can be manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, and, in some cases, pulmonary edema, bradycardia, hypotension, partial or complete airway obstruction, atypical snoring, and death. If you are taking this once daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Concomitant use of Demerol Injection with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could decrease meperidine plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to meperidine. Your doctor will pass the scope through your bladder and ureter into your kidney. She uses a small basket to remove small stones. If the stones are larger, the doctor will pass a laser through the scope to break them up. Typically, you are able to go home on the same day. Carpuject are packaged in a Slim-Pak tamper detection package. Note that a needle is not included. What should I avoid while taking tolterodine Detrol? To prevent constipation, eat a diet adequate in fiber, drink plenty of water, and exercise. If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative such as a stimulant-type with stool softener. cyclosporin where to purchase otc
Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. Warn patients of the symptoms of serotonin syndrome and to seek medical attention right away if symptoms develop. This medication may lower your ability to fight infections. This may make you more likely to get a serious rarely fatal infection or make any infection you have worse. Meperidine produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation. Ureteroscopy: This procedure treats stones in the kidneys and ureters. Your doctor uses a thin, flexible scope to find and remove stones. To prevent needle-stick injuries, needles should not be recapped, purposely bent, or broken by hand. Studies to determine the effect of meperidine on fertility have not been conducted. Demerol Injection is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Adverse outcomes in pregnancy can occur regardless of the health of the mother or the use of medications. Because the duration of opioid reversal is expected to be less than the duration of action of meperidine in Demerol Injection, carefully monitor the patient until spontaneous respiration is reliably re-established. If the response to an opioid antagonist is suboptimal or only brief in nature, administer additional antagonist as directed by the product's prescribing information. Inadvertent injection about a nerve trunk may result in sensory-motor paralysis which is usually, though not always, transitory. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Report prolonged or to your doctor. Think about stirring up your favorite drink from a powder mix. These are the most common ones. The concomitant use of Demerol Injection with all cytochrome P450 3A4 inhibitors may result in an increase in meperidine plasma concentrations, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression. In addition, discontinuation of a concomitantly used cytochrome P450 3A4 inducer may result in an increase in meperidine plasma concentration. This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages. buy warticon venezuela
Meperidine is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioid-induced respiratory depression in the neonate. Demerol Injection is not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate. Opioid analgesics, including Demerol Injection, can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions. However, this effect is not consistent and may be offset by an increased rate of cervical dilation, which tends to shorten labor. Monitor neonates exposed to opioid analgesics during labor for signs of excess sedation and respiratory depression. Swallow Detrol LA extended-release capsules whole. Do not break, crush, or chew before swallowing. If concomitant use is necessary, consider increasing the Demerol Injection dosage until stable drug effects are achieved. Monitor for signs of opioid withdrawal. If a CYP3A4 or CYP2B6 inducer is discontinued, consider Demerol Injection dosage reduction and monitor for signs of respiratory depression. Blurred vision; constipation; dizziness; drowsiness; dry eyes; dry mouth; headache; indigestion; stomach pain. You need to get the condition treated. If your bladder can't empty, that can lead to infections and other problems. Take this by as directed by your doctor, usually with food or milk. Follow your dosing instructions carefully. The dosage and length of treatment are based on your medical condition and response to treatment. Different dosing schedules exist for this medication. If you are not taking the same dose each day or if you take this medication every other day, it may help to mark your calendar with a reminder. Consult your doctor or if you have any questions. Detrol LA extended-release capsules works best if it is taken at the same time each day. The treatment takes about an hour, and you can usually go home about an hour later. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company. Elderly patients aged 65 years or older may have increased sensitivity to meperidine. In general, use caution when selecting a dosage for an elderly patient, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. What are the possible side effects of tolterodine Detrol?
Chronic use of opioids may influence the hypothalamic-pituitary-gonadal axis, leading to androgen deficiency that may manifest as low libido, impotence, erectile dysfunction, amenorrhea, or infertility. Cut back on sodium and salty foods: Lots of sodium can raise calcium levels in your urine. And that can cause stones to form. Ask your pharmacist about the safe use of those products. The potential for these risks should not, however, prevent the proper management of pain in any given patient. Patients at increased risk may be prescribed opioids such as Demerol Injection, but use in such patients necessitates intensive counseling about the risks and proper use of Demerol Injection along with intensive monitoring for signs of addiction, abuse, and misuse. Abuse and addiction are separate and distinct from physical dependence and tolerance. Health care providers should be aware that addiction may not be accompanied by concurrent tolerance and symptoms of physical dependence in all addicts. In addition, abuse of opioids can occur in the absence of true addiction. If concomitant use of acyclovir and Demerol Injection is necessary, monitor patients for respiratory depression and sedation at frequent intervals. Tolterodine reduces spasms of the bladder muscles. Talk to your doctor or about lifestyle changes that might benefit you. Chronic use of opioids may cause reduced fertility in females and males of reproductive potential. This medicine may cause bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. The findings cannot be clearly attributed to maternal toxicity. antabuse
Demerol Injection contains meperidine, a Schedule II controlled substance. There is a relationship between increasing meperidine plasma concentration and increasing frequency of dose-related opioid adverse reactions such as nausea, vomiting, CNS effects, and respiratory depression. Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use. Presentation of adrenal insufficiency may include non-specific symptoms and signs including nausea, vomiting, anorexia, fatigue, weakness, dizziness, and low blood pressure. If adrenal insufficiency is suspected, confirm the diagnosis with diagnostic testing as soon as possible. If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. Wean the patient off of the opioid to allow adrenal function to recover and continue corticosteroid treatment until adrenal function recovers. Other opioids may be tried as some cases reported use of a different opioid without recurrence of adrenal insufficiency. The information available does not identify any particular opioids as being more likely to be associated with adrenal insufficiency. UCSF Medical Center: "Nutrition Tips for Inflammatory Bowel Disease. This may interfere with certain laboratory tests such as possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Consult your doctor for specific advice.
Overdose symptoms may include dry mouth, blurred vision, and fast heartbeat. If Demerol Injection is abruptly discontinued in a physically-dependent patient, a withdrawal syndrome may occur. Some or all of the following can characterize this syndrome: restlessness, lacrimation, rhinorrhea, yawning, perspiration, chills, myalgia, and mydriasis. Other signs and symptoms also may develop, including: irritability, anxiety, backache, joint pain, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea, or increased blood pressure, respiratory rate, or heart rate. See USP Controlled Room Temperature. Candesartan belongs to a class of drugs called angiotensin receptor blockers ARBs. It works by relaxing vessels so can flow more easily. The stones can be brown or yellow, and smooth or rough. Side Effects List Detrol LA side effects by likelihood and severity. Inform your doctor if your condition persists or worsens. What other drugs will affect tolterodine Detrol LA? Individually titrate Demerol Injection to a dose that provides adequate analgesia and minimizes adverse reactions. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Carbon dioxide CO 2 retention from opioid-induced respiratory depression can exacerbate the sedating effects of opioids. DEMEROL is not a trademark of Hospira. Although may be used to prevent problems or treat people who have problems, it may also rarely cause serious kidney problems or make them worse. Your doctor will check your kidney function while you are taking candesartan. Tell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine. The major hazards of meperidine, as with other opioid analgesics, are respiratory depression and, to a lesser degree, circulatory depression; respiratory arrest, shock, and cardiac arrest have occurred. canada meds actonel
This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. Because of these risks, reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. First, you complete a chart of the times you pee and the times you leak. You observe patterns and then plan to empty your bladder before an accident would happen. You can also "retrain" your bladder, gradually increasing the time between bathroom visits. Kegel exercises are also helpful. Demerol Injection may cause severe hypotension including orthostatic hypotension and syncope in ambulatory patients. How does your doctor know if you really do have a kidney stone? Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. It may be taken with or without food. The dosage is based on your medical condition and response to therapy. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines such as cetirizine, diphenhydramine drugs for sleep or anxiety such as alprazolam, diazepam, zolpidem muscle relaxants, and narcotic pain relievers such as codeine. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using tolterodine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems heart failure, slow heartbeat, QT prolongation in the EKG family history of certain heart problems QT prolongation in the EKG, sudden cardiac death.
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See "What Are Side Effects Associated with Using Tolterodine? It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding. Consult your pharmacist for further advice. To relieve dry mouth, suck sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. setim.info evista
Tell your doctor if your condition does not improve or if it worsens such as your remain high or increase. Meperidine may enhance the neuromuscular blocking action of skeletal muscle relaxants and produce an increased degree of respiratory depression. Parenteral drug abuse is commonly associated with transmission of infectious diseases such as hepatitis and HIV. Demerol Injection is indicated for preoperative medication, support of anesthesia, and obstetrical analgesia. Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs.
PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Detrol LA extended-release capsules while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Detrol LA extended-release capsules. Meperidine and normeperidine are excreted by kidneys. Flecainide can affect your heart's rhythm. Other drugs can have the same effect.
It is unknown if this drug passes into milk. Consult your doctor before -feeding. In severe overdose, particularly by the intravenous route, apnea, circulatory collapse, cardiac arrest, and death may occur. Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. If necessary, meperidine may be given intravenously, but the injection should be given very slowly, preferably in the form of a diluted solution. Rapid intravenous injection of narcotic analgesics, including meperidine, increases the incidence of adverse reactions; severe respiratory depression, apnea, hypotension, peripheral circulatory collapse, and cardiac arrest have occurred. Meperidine should not be administered intravenously unless a narcotic antagonist and the facilities for assisted or controlled respiration are immediately available. When meperidine is given parenterally, especially intravenously, the patient should be lying down.